Emerging technologies such as advanced analytics, robotics, and automation promise significant rewards for the pharmaceutical industry, including increased speed, compliance, cost savings, and product...
Biologics are expressed from the hosts of bacterial, yeast, animal cells, and continuous cell lines. As biological products are produced from a cell substrate, it is inevitable that residual host cel...
Plasmid DNA (pDNA) are applied for gene therapy and vaccine development. The purification of DNA plasmids is difficult, because supercoiled pDNA (the product) is quite similar in size and structure to...
Adventitious agent contaminants in seed stocks, cell substrates, and raw materials used in the production of biological products include bacteria, fungi, mycoplasma, mycobacteria, and viruses. Effecti...
Recombinant proteins are primarily expressed in host cells, such as bacteria, yeast, mammalian, insect, or plant cell lines. During the bioproduction process, these host cells also produce by-product ...
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